@article{oai:ndu-rep.repo.nii.ac.jp:00001240,
 author = {那須, 優則},
 journal = {日本歯科大学紀要. 一般教育系, Bulletin of the Nippon Dental University. General education},
 month = {Mar},
 note = {application/pdf, Edaravone (3-methyl-1-phenyl-2-pyrazolin-5-one [MW:174.20]) is a free radical scavenger clinically used as a brain protective agent in cerebral infarction. In the acute phase of cerebral infarction, it shows cerebroprotective effects by suppressing the action of reactive oxygen species around the infarction site,
including the penumbra region, and preventing oxidative damage to endothelial cells and nerve cells in the brain. As a result, it inhibits the onset and exacerbation of ischemic cerebrovascular disorders such as cerebral edema, cerebral infarction, and neurological syndromes. In this study, we focused on the free radical scavenging ability of edaravone to reduce the effects of radiation and its damage. We examined the effect of edaravone on proliferation of human umbilical vein endothelial cells X-ray irradiated. Consequently, we found that the addition of edaravone ameliorated the cellular growth of HUVECs irradiated 5 Gy of X-rays.},
 pages = {21--27},
 title = {エダラボンのヒト臍帯静脈内皮細胞に対する放射線防護作用},
 volume = {52},
 year = {2023},
 yomi = {ナス, マサノリ}
}